The University of Pretoria Convention. Kinda like dragonfire except, fewer role-players, more Magic players and Wargamers, no LARPS and runs ever so slightly more to schedule - however they don't write their own modules, so that's one less issue they have to deal with...
Update: Upcon 2008
Judging by their current Facebook page for the latest offering, they have started to write their own modules... Still no LARPS, though.
http://www.facebook.com/event.php?eid=25521660009&ref=nf
Update: Post-Upcon 2008
Ok, they had a LARP there this year. They also had a fair turnout of role-players, probably more than at Dragonfire these days. Wargaming is still pretty large there, but they sensibly tucked the magic players away into a back room.